Star Trek: Infinite is a grand strategy experience that lets you play your own Star Trek story as the leader of one of four major factions in the galaxy. Follow the specially crafted story or blaze your own trail in the first Star Trek grand strategy game.
Looks like Paradox is making a Stellaris-based Star Trek grand strategy game!
Have you tried the Star Trek mod for Sins of a Solar Empire? I had quite a bit of fun with that one.
I have not, it’s been a while since I’ve played sins, sounds like a fun excuse to revisit!