I often hear about the original “Elite” in this context. It managed to do real time 3d rendering on home computers (albeit wireframe) in a time when that was usually relegated to pre-renders or supercomputers. Came out a good decade before making 3d games was more generally viable.
There is the Anno series of games, which are technically RTS games but if I’m honest I find them the most fun when I go out of my way to avoid combat/micromanagement. I’ve only played 1404, 2070, and 2205, 2070 being the best in my opinion, but it has a bad history with DRM so I’d suggest 1404 (known as “Dawn of Discovery” in the US because us americans are afraid of numbers apparently).
Edit: looking at the steam page it looks like they decided to take 1404 down and made a new page where the game is (mostly) unchanged besides requiring you to jump through all the BS hoops that 2070 did, so I’d say if you’re gonna spend money get 1404 on GOG, or if you are willing to do unspeakable things go with 2070.