Arguably. Maybe.

My understanding is the predictions of alpha fold are always verified with the slower, more accurate process - if the predictions from alpha fold showed something promising.

Its main use was to help identify directions to further investigate. Not to blindly take the protein structure it predicted.

So there might be initial bias in terms of the how possibilities are narrowed, but you can certainly use it to do real science.

They are depreciating due to market forces (upgrades), but the data centers and hubs of gpus are infrastructure in a similar way that fiber and rails were in the other bubbles. I think the comparison stands. They all age to some extent, but gpus depreciate in value faster because nvidia is always marketing the next generation, not because they physically degrade that fast.

I say this as someone genially against the rapid construction of new data centers btw.